Mapedit [IA][Direct] -
A WYSIWYG imagemap editor for Microsft Windows and Unix. Supports both client- and server-side imagemaps. 2.0 for Windows can map GIF, JPEG and PNG-format images.
MapMaker [IA][Direct] -
Allows you to create an imagemap for any in-line image anywhere on the World Wide Web.
MapServe [IA][Direct] -
Imagemapping cgi program for use with MacHTTP.